I hold a BSc (hons) in Genetics and Biochemistry from Queen’s University, Belfast and followed this with an MSc in Molecular Biology from The University of Dundee. My PhD was undertaken at University College London and largely focused on characterisation of drug-induced apoptosis and associated gene expression changes in cell lines and samples from leukemic patients. I have also experience of working in industry, within the drug safety department of a Contract Research Organisation.
I started my OU journey on 2005 as an Associate Lecturer/ tutor teaching on interdisciplinary science and biological modules at all levels of undergraduate study and I still tutor on the Level 3 project module SXL390. I hold a Senior Fellowship from the Higher Education Academy (now known as AdvanceHE). I have been working as a staff tutor in the school of Life, Health and Chemical Sciences (LHCS) since 2018, supporting over 30 ALs to deliver effective tuition to distance learners.
I am Module Chair on S317 Biological science: from genes to species and I am also the Student Support Team (SST) lead for LHCS. In this role I collaborate with colleagues across the University to develop the support we provide for our students via enhancing shared understanding between tutors, academic colleagues and the SST.
I am passionate about enhancing academic community and am also involved in initiatives such as producing the school newsletter, working with buddies and student interns and providing opportunities for development of student online confidence and skills via Online Journal Club (OJC).
Co-lead on project to evaluate use of zero grades in assessment: An evaluation of use and impact of zero grades in assessment; are we being consistent, fair, and transparent?
Co-lead on a project introducing and evaluating a novel model of Online Journal Club: Online journal clubs in distance higher education: an opportunity to develop skills and community?
Co-lead on a project exploring usage and experience of Individual Student Support Sessions (ISSS): STEM ISSS - where are we now? Evaluating awareness, usage and effectiveness of individual student support sessions
Part of the project team on a project evaluating the experience of Credit Transfer students: Improving success and satisfaction of credit transfer students entering L3 modules in Science
Part of the project team on a project introducing and evaluating journal clubs within secure environments: Summer Series of Journal Clubs: an opportunity to develop employability skills and a sense of community amongst students in secure environments
Lab-based Research Publications (maiden name Riordan)
Harrison CJ, Griffiths M, Moorman F, Schnittger S, Cayuela JM, Shurtleff S, Gottardi E, Mitterbauer G, Colomer D, Delabesse E, Castéras V: A multicenter evaluation of comprehensive analysis of MLL translocations and fusion gene partners in acute leukemia using the MLL FusionChip device. Cancer Genet Cytogenet. 173:17-22, 2007.
Mengubas K, Riordan FA, Bravery CA, Lewin J, Owens DL, Mehta AB, Hoffbrand AV, Wickremasinghe RG: Ceramide-induced killing of normal and malignant human lymphocytes is by a non-apoptotic mechanism. Oncogene 18:2499, 1999
Riordan FA, Wickremasinghe RG: Signal transduction by the Philadelphia chromosome-encoded BCR/ABL Oncoproteins: Therapeutic Implications for Chronic Myeloid Leukemia and Philadelphia-positive Acute Lymphoblastic Leukemia. Hematology 3:387-396, 1998.
Riordan FA, Bravery CA, Mengubas K, Ray N, Borthwick NJ, Akbar AN, Hart SM, Hoffbrand AV, Mehta AB, Wickremasinghe RG: Herbimycin A accelerates the induction of apoptosis following etoposide treatment or gamma-irradiation of bcr/abl-positive leukaemia cells. Oncogene 16:1533, 1998
Riordan FA, Foroni L, Hoffbrand AV, Mehta AB, Wickremasinghe RG: Okadaic acid-induced apoptosis of HL60 leukemia cells is preceded by destabilization of bcl-2 mRNA and downregulation of bcl-2 protein. FEBS Letters 435:195, 1998
Mengubas K, Riordan FA, Hoffbrand AV, Wickremasinghe RG: Co-ordinated downregulation of bcl-2 and bax expression during granulocytic and macrophage-like differentiation of the HL60 promyelocytic leukaemia cell line. FEBS Letters 394:356, 1996
Riordan FA, Bhattacharyya A, McAteer S, Lilley DMJ: Kinking of RNA helices by bulged bases, and the structure of the human-immunodeficiency-virus transactivator response element. Journal of Molecular Biology 226:305, 1992