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Dr Radka Gromnicova

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Professional biography

Radka Gromnicova is a technician working in the Electron Microscopy Suite. She works with OU students, academics and external customers helping them analyse their sample using electron microscopy.

Radka believes that speed, quality and communication is crucial to the process of taking a “raw” sample and finding out more about it.

She has experience of sample preparation for transmission electron microscopy and operating the microscope in advanced imaging or determining elemental composition. Her specialization is in the biological samples and nanoparticle preparations. Moreover, she is also involved in supervising a PhD student.

Radka also holds a PhD in biological sciences, her thesis was titled “Gold nanoparticles as a delivery system of oligonucleotides into the brain.” During her PhD she gained experience in cell culture, histology and nanomaterial preparation.

Research interests

  • developing new techniques and protocols for electron microscopy
  • gold nanoparticles in biological systems for oligonucleotide delivery
  • 3D model of blood-brain barrier

Teaching interests

  • TEM operation
  • preparation of samples for TEM
  • STEM

Impact and engagement

The Electron Microscopy Suite is gaining wider reach for its services via a new webpage that we set up to engagement with our business and academic partners via newsletters and social media.

Publications

Nanocarriers for Delivery of Oligonucleotides to the CNS (2022)
Male, David and Gromnicova, Radka
International Journal of Molecular Sciences, 23, Article 760(2)


Investigating the effect of N-doping on carbon quantum dots structure, optical properties and metal ion screening (2022)
Nguyen, Kiem Giap; Baragau, Ioan-Alexandru; Gromnicova, Radka; Nicolaev, Adela; Thomson, Stuart A. J.; Rennie, Alistair; Power, Nicholas P.; Sajjad, Muhammad Tariq and Kellici, Suela
Scientific Reports, 12(1) (p 13806)


Age-related ultrastructural neurovascular changes in the female mouse cortex and hippocampus (2021-05)
Frias Anaya, Eduardo; Gromnicova, Radka; Kraev, Igor; Rogachevsky, Vadim; Male, David; Crea, Francesco; Hawkes, Cheryl and Romero, Ignacio A.
Neurobiology of Aging, 101 (pp. 273-284)


Tissue distribution and cellular localization of gold nanocarriers with bound oligonucleotides (2021-04)
Fatima, Nayab; Akcan, Ugur; Kaya, Mehmet; Gromnicova, Radka; Loughlin, Jane; Sharrack, Basil and Male, David
Nanomedicine, 16(9) (pp. 709-720)


Gold nanocarriers for transport of oligonucleotides across brain endothelial cells (2020)
Fatima, Nayab; Gromnicova, Radka; Loughlin, Jane; Sharrack, Basil and Male, David
PLOS ONE, 15, Article e0236611(9)


PPARγ agonist-loaded PLGA -PEG nanocarriers as a potential treatment for Alzheimer’s disease: in vitro and in vivo studies (2018-09-20)
Silva-Abreu, Marcelle; Calpena, Ana Cristina; Benito, Pol Andres; Romero, Ignacio A.; Roig-Carles, David; Gromnicova, Radka; Espina, Marta; Ferrer, Isidre; Garcia, Maria Luisa and Male, David
International Journal of Nanomedicine, 13 (pp. 5577-5590)


Transport of Gold Nanoparticles by Vascular Endothelium from Different Human Tissues (2016-08-25)
Gromnicova, Radka; Kaya, Mehmet; Romero, Ignacio A.; Williams, Phil; Satchell, Simon; Sharrack, Basil and Male, David
PLoS ONE, 11, Article e0161610(8)


Localisation and mobility of glucose-coated gold nanoparticles within the brain (2016-03-31)
Gromnicova, Radka; Yilmaz, Canan Ugur; Orhan, Nurcan; Kaya, Mehmet; Davies, Heather; Williams, Phil; Romero, Ignacio A.; Sharrack, Basil and Male, David
Nanomedicine, 11(6) (pp. 617-625)


A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactions (2016-01-21)
Reddy, P; Gromnicova, Radka; Davies, Heather; Phillips, James; Romero, Ignacio A and Male, David
F1000Research, 4, Article 1279


Zinc-imidazolate polymers (ZIPs) as a potential carrier to brain capillary endothelial cells (2015-10-26)
Chiacchia, M.; Cerutti, C.; Gromnicova, R.; Rietdorf, K.; Romero, I.A. and Bradshaw, D.
Journal of Materials Chemistry B, 3(46) (pp. 9053-9059)


Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro (2013-12-05)
Gromnicova, Radka; Davies, Heather A.; Sreekanthreddy, Pedagannganagari; Romero, Ignacio A.; Lund, Torben; Roitt, Ivan M.; Phillips, James B. and Male, David K.
PLoS ONE, 8, Article e81043(12)


Transcriptional control of the multi-drug transporter ABCB1 by transcription factor Sp3 in different human tissues (2012-10)
Gromnicova, Radka; Romero, Ignacio A and Male, David
PLoS ONE, 7, Article e48189(10)


Gold nanoparticles for imaging and drug transport to the CNS (2016)
Male, David; Gromnicova, Radka and Mcquaid, Conor
In: Al-Jamal, Khuloud ed. Nanotechnology and the Brain. International Review of Neurobiology (130) (pp. 155-189)
ISBN : 978-0-12-804636-4 | Publisher : Elsevier | Published : London


Gold Nanoparticles as a Delivery System of Oligonucleotides into the Brain (2017-03-03)
Gromnicova, Radka
PhD thesis The Open University