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Dr Toni Gladding

Profile summary

  • Central Academic Staff
  • Senior Lecturer
  • Faculty of Science, Technology, Engineering & Mathematics
  • School of Engineering & Innovation
  • toni.gladding

Research Activity

Externally funded projects

Detection and Characterisation of Inflammatory Agents Associated with Bioaerosol Emitted from Biowaste and Intensive Agriculture

RoleStart dateEnd dateFunding source
Lead01/Jan/201531/Dec/2018NERC (Natural Environment Research Council)
This project focuses on detection and characterisation of inflammatory agents in bioaerosol emitted from biowaste and intensive agriculture. It is known that cellular components (e.g. endotoxin and glucan) are emitted by composting and farming. Endotoxin binds to receptors associated with many cell types generating pro-inflammatory cytokines, resulting in inflammatory response in exposed people. Endotoxin has advantages as a bioaerosol metric – it is: • detectable through robust methods • a broad-spectrum indicator of bacterially-derived (Gram negative) bioaerosol • the only bioaerosol component for which an exposure limit to protect the general population is currently realistic. Whilst promising, only a small database exists of endotoxin concentrations around composting / farming facilities and little is known about exposure of the general population (as opposed to occupational exposure). Little knowledge exists on the size fractions that airborne endotoxin is associated with, the relative importance of whole cells (live/dead), vesicles and disrupted fragments, or its dispersion properties. Although robust detection methods exist, there are presently no rapid or continuous detection methods available.

Publications

A study of the potential release of bioaerosols from containers as a result of reduced frequency residual waste collections (2017-01-15)
Gladding, Toni L. and Gwyther, Ceri L.
Science of the Total Environment, 576 (pp. 481-489)
Waste electrical and electronics equipment: do new regulations promote sustainability? (2008-12)
Gladding, Toni
International Journal of Performability Engineering, 4(4) (pp. 319-332)
Organic dust exposure and work-related effects among recycling workers (2003-06)
Gladding, Toni; Thorn, Jorgen and Stott, David
American Journal of Industrial Medicine, 43(6) (pp. 584-591)
Environment management report. Focus on Waste Management (2006)
Yoxon, Mark; Burnley, Stephen and Gladding, Toni
ISBN : 0-580-48412-2 | Publisher : British Standards Institution | Published : London
Health risks of materials recycling facilities (2002-11)
Gladding, T.L.
In: Hester, R.E. and Harrison, R.M. eds. Environmental and health impact of solid waste management activities. Issues in environmental science and technology (18) (pp. 53-72)
ISBN : 854042857 | Publisher : Royal Society of Chemistry | Published : Cambridge, UK
Greenhouse gas emissions from non-recyclable residual household waste within domestic wheeled bins (2015-10-05)
Boardman, C.; Burnley, S.; Gauci, V. and Gladding, T.
In : 15th International Waste Management and Landfill Symposium (Sardinia 2015) (5-9 October 2015, S. Margherita di Pula, Sardinia, Italy)
Monitoring bioaerosol and odour emissions from composting facilities - WR1121 (2013-08-20)
Williams, Melanie; Lamarre, Baptiste; Butterfield, David; Tyrrel, Sean; Longhurst, Phil; Drew, Gillian; Al-Ashaab, Reyna; Nelson, Alan; Gladding, Toni; Simpson, Annika; Coughlin, Toni and Hansell, Anna
DEFRA, London.
Evidence: Biofilter performance and operation as related to commercial composting (2013-04)
Frederickson, J.; Boardman, C. P.; Gladding, T. L.; Simpson, A. E.; Howell, G. and Sgouridis, F.
Environment Agency, Bristol.
Scoping study of potential health effects of fortnightly residual waste collection and related changes to domestic waste systems (2009-07)
Gladding, Toni
Waste Resources Action Programme

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