I graduated from Cambridge University with an MA in Natural Sciences, this was then followed by an MSc in Chemistry at Imperial College and a PhD in Organometallic Chemistry from Kings College London in 2003. Since then I have further done research in inorganic chemistry in France (CEA, Grenoble), been a teaching fellow at Sheffield University and prior to joining the OU in June 2015 was a Senior Lecturer in Chemistry and Course Leader in Pharmaceutical Sciences at London Metropolitan University for 8 years. I am also an associate editor for the journal RSC Advances.
My research interests primarily involve exploiting electrohydrodynamic techniques (electrospinning and electrospraying) to generate nanomaterials. Our research in this area predominantly focuses on using these techniques to fabricate novel drug delivery systems. The materials generated generally increase the solubility of poorly soluble drug molecules thereby increasing their bioavailability. In addition we have fabricated materials that can tuned to give either sustained or pulsatile release of drug cargo. We are also interested in luminescent solids with unusual optical properties produced via similar techniques to generate highly-tuned materials that act as sensitive sensors of gas molecules. Recent work has applied similar techniques to generate anti-microbial materials for the food industry using food waste as a raw material. This work is supported by the BBSRC.
I have over 10 years experience of face-to-face teaching (lectures, tutorials etc) at UK universities and joined the OU to gain experience in developing and utlizing distance learning approaches to teach HE level chemistry. Since joining the OU in 2015 I have written material for S111, S315 and SS002 and am currently on the production team for the second new stage one module, S112. In addition I am a member of the presenting module team for S315 providing support for various inorganic chemistry sections and an online interactive practical on drug-drug interactions and also on S111. I am also employed as an associate lecturer on the project module SXM390. Additionally, I developed support for materials for chemistry students transitioning between stages in their study, authoring the material for the "Get Ready For S215" website.
Dr Gareth Williams (UCL, School of Pharmacy)
Dr Samir Nuseibeh (Imperial College, Faculty of Medicine)
Dr Kenneth White (London Metropolitan University, School of Human Sciences)
Dr Gemma Shearman (Kingston University, Pharmacy and Chemistry)
Prof Graham Bonwick (Newcastle University, Fera Science Ltd)
Prof Deng-Guang Yu (Shanghai University of Science and Technology)
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Simon Collinson (Life Health & Chemical Sciences, Open University) and Nick Chatterton (Life Health & Chemical Sciences, Open University), with external collaborators at Newcastle University, Biopower Technologies Ltd, and Marks and Spencer plc A total of ca. £24K funding has been secured to support a 4 month project on the formulation and testing of crop by-product nanomaterials which incorporate anti-microbial bioactive compounds for potential usage in food grade materials and extension of their shelf-life. The work will involve electrospinning of mechanically processed crop by-products blended with other biodegradable natural polymers such as alginic acid or chitosan. The porosity of these materials will be further optimized by chemical or enzymatic processes, followed by studies on the encapsulation and controlled release of the bioactives. The anti-microbial and antioxidant activity of the bioactive-loaded nanomaterials will also be assessed. As well as the food industry, the materials are envisaged for potential use in the personal care products, pharmaceuticals and surface coatings.
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|Co-investigator||04/Jul/2016||26/Aug/2016||IB Carb Network|
This is a pilot research project for an undergraduate student. The project builds on my previous research functionalizing the carbohydrates starch and chitosan to produce new functional materials. This project will support proteases on chitosan to produce recyclable and stable catalysts for the hydrolysis of protein wastes to more valuable hydrolysates. WRAP has estimated waste in the food and drinks supply chain (WRAP 01 312 PAD102-308) reporting that ‘about 2.25 million tonnes of material are rendered each year to produce around 500,000 tonnes of protein meal.’ This example represents an important biorefinery resource for valuable proteins, peptides and amino acids. Protein containing wastes arise from several food industries and the focus here will be from cheese production (whey protein), connective tissue (the protein collagen which yields gelatin), and eggs (ovalbumin). The hydrolysates from waste proteins often display improved antioxidant properties compared to the protein and this will be also studied.
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